Journal article
Cyclobutanes in catalysis.
- 2011-07-28
Published in:
- Angewandte Chemie (International ed. in English). - 2011
English
The exploitation of ring strain as a driving force to facilitate chemical reactions is a well-appreciated principle in organic chemistry. The most prominent and most frequently used compound classes in this respect are oxiranes and cyclopropanes. For rather a long time, cyclobutanes lagged behind these three-membered-ring compounds in their development as reactive substrates, but during the past decade an increasing number of useful reactions of four-membered-ring substrates have emerged. This Minireview examines corresponding catalytic reactions ranging from Lewis or Brønsted acid catalyzed processes to enzymatic reactions. The main focus is placed on transition-metal-catalyzed C-C bond-insertion and β-carbon-elimination processes, which enable exciting downstream reactions that deliver versatile building blocks.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1002/anie.201101053
- PMID 21793133
- Persistent URL
- https://fredi.hepvs.ch/global/documents/67982
Statistics
Document views: 39
File downloads: