Journal article
Uterine responses to the preattachment embryo in domestic ungulates: recognition of pregnancy and preparation for implantation.
- Bauersachs S Animal Physiology, Institute of Agricultural Sciences, Department of Environmental Systems Science, ETH Zurich, 8092 Zurich, Switzerland; email: stefan.bauersachs@usys.ethz.ch.
- Wolf E
- 2014-11-12
Published in:
- Annual review of animal biosciences. - 2015
RNA-seq
endometrium
female fertility
microarray
reproduction
transcriptome
Animals
Blastocyst
Cattle
Embryo Implantation
Endometrium
Female
Gene Expression Regulation
Gene Ontology
Horses
Humans
MicroRNAs
Pregnancy
Pregnancy, Animal
Species Specificity
Swine
Transcriptome
English
The endometrium is a tissue newly evolved with the development of mammalian species. Its main function is the support of embryonic growth and development and the nutrition of the fetus. The species-specific differences in establishment and maintenance of pregnancy make the study of this tissue in various mammalian organisms particularly interesting. With the application of omics technologies to various mammalian species, many systematic studies of endometrial gene expression changes during the phase of establishment of pregnancy have been performed to obtain a global view of regulatory events associated with this biological process. This review summarizes the results of trancriptome studies of bovine, porcine, and equine endometrium. Furthermore, the results are compared between these species and to humans. Because an increasing number of studies suggest an important role of small regulatory RNAs (i.e., microRNAs), recent findings related to the regulation of endometrial functions and the development of the conceptus are presented.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1146/annurev-animal-022114-110639
- PMID 25387113
- Persistent URL
- https://fredi.hepvs.ch/global/documents/283850
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