Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA.

• Hou Y Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Pinheiro J Department of Pathology, Centro Hospitalar São João, Porto, Portugal.
• Sahm F Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Reuss DE Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Schrimpf D Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Stichel D Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Casalini B Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Koelsche C Department of General Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Sievers P Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Wefers AK Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Reinhardt A Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Ebrahimi A Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Fernández-Klett F Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Pusch S Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Meier J Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Schweizer L Department of Neuropathology, Charité, Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin, and Humboldt-Universität Zu Berlin, Berlin Institute of Health, Berlin, Germany.
• Paulus W Institute of Neuropathology, University Hospital Münster, Münster, Germany.
• Prinz M Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.
• Hartmann C Department of Neuropathology, Medizinische Hochschule Hannover, Hannover, Germany.
• Plate KH Department of Neuropathology, University Hospital Frankfurt, Frankfurt, Germany.
• Reifenberger G Department of Neuropathology, University Hospital Düsseldorf, Düsseldorf, Germany.
• Pietsch T Department of Neuropathology, University of Bonn, Bonn, Germany.
• Varlet P Department of Neuropathology, Hôpital Sainte-Anne, Université Paris V Descartes, Sorbonne Paris Cité, Paris, France.
• Pagès M Department of Neuropathology, Hôpital Sainte-Anne, Université Paris V Descartes, Sorbonne Paris Cité, Paris, France.
• Schüller U Department of Neuropathology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
• Scheie D Department of Pathology, Rigshospitalet, Copenhagen, Denmark.
• de Stricker K Department of Pathology, Rigshospitalet, Copenhagen, Denmark.
• Frank S Division of Neuropathology, Department of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.
• Hench J Division of Neuropathology, Department of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.
• Pollo B Department of Neuropathology, Neurological Institute Besta, Milan, Italy.
• Brandner S Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, and, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
• Unterberg A Division of Experimental Neurosurgery, Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany.
• Pfister SM Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
• Jones DTW Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
• Korshunov A Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
• Wick W Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
• Capper D Department of Neuropathology, Charité, Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin, and Humboldt-Universität Zu Berlin, Berlin Institute of Health, Berlin, Germany.
• Blümcke I Department of Neuropathology, University Hospital Erlangen, Erlangen, Germany.
• von Deimling A Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany. andreas.vondeimling@med.uni-heidelberg.de.
• Bertero L Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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DNA methylation

NOTCH1

PRKCA

Papillary glioneuronal tumor

RNA sequencing

SLC44A1

Adolescent

Adult

Antigens, CD

Biomarkers, Tumor

Brain

Brain Neoplasms

Child

Cohort Studies

Female

Gene Fusion

Humans

Male

Middle Aged

Neoplasms, Neuroepithelial

Organic Cation Transport Proteins

Protein Kinase C-alpha

Site-Specific DNA-Methyltransferase (Adenine-Specific)